Volta

Revisiting the Potential Role of Urine in Wastewater Surveillance for COVID-19 and Beyond

High Resolution Image Download MS PowerPoint Slide The overperformance of wastewater testing during near-source surveillance, especially in venues where defecation is presumed to be de minimis, such as aircraft and nonresidential schools, suggests the possibility of a non-fecal source. To revisit the possibility of urine as an input, data were compiled from 45 studies on SARS-CoV-2 RNA in the urine of 1924 COVID-19 patients. In general, the reporting quality was extremely low. The estimated pooled prevalence of urinary SARS-CoV-2 RNA shedding is 11.3% (95% CI: 8.4–14.3), which roughly agrees with previous reviews. However, the 2-fold prediction interval and wide range of observed prevalences warrant careful consideration of the variability between studies. Among the eight studies reporting sufficient methodological details to …

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