Volta

Detection of several respiratory viruses with Surface-Enhanced Raman Spectroscopy coupled with Artificial Intelligence

Unknown authors · 2023
hash_id: 1f472e85d65e59446a1109e284d11fed3fa68426e63eebb20de3d3028b27568a · DOI: 10.1016/j.clispe.2023.100025

Diagnoses of viral infections are a challenge when facing a crisis like COVID-19, where their speed and reliability are critical to minimize diseases spread. The gold standard of diagnostics, quantitative Polymerase Chain Reaction, is time- and reagent-consuming and requires qualified personnel. Therefore, it is necessary to find new detection techniques to overcome these barriers. Surface Enhanced Raman Spectroscopy (SERS) is a detection method, based on light and metallic particles admixed with the samples, already used in different fields of research. In this study, we discriminate three respiratory viruses using a combination of SERS and Artificial Intelligence (AI). Our technique appears to be fast, reproducible, and reliable, achieving between 95% and 100% of accuracy, standing out as a powerful tool usable …

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Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection secondary