Volta

Babies, bugs and brains: How the early microbiome associates with infant brain and behavior development

Unknown authors · 2023
hash_id: 716e939e8fa357b89a2f62d1992b72f17e06a367d2798033a15d420a870a7653 · DOI: 10.1371/journal.pone.0288689

Growing evidence is demonstrating the connection between the microbiota gut-brain axis and neurodevelopment. Microbiota colonization occurs before the maturation of many neural systems and is linked to brain health. Because of this it has been hypothesized that the early microbiome interactions along the gut-brain axis evolved to promote advanced cognitive functions and behaviors. Here, we performed a pilot study with a multidisciplinary approach to test if the microbiota composition of infants is associated with measures of early cognitive development, in particular neural rhythm tracking; language (forward speech) versus non-language (backwards speech) discrimination; and social joint attention. Fecal samples were collected from 56 infants between four and six months of age and sequenced by shotgun metagenomic sequencing. Of these, 44 performed …

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Gut-Brain Axis in the Early Postnatal Years of Life: A Developmental Perspective secondary