Volta

Open questions and recent advances in the control of a multi‐host infectious disease: animal tuberculosis

Abstract Animal tuberculosis (TB) control is globally important for public health, economics and conservation. Wildlife species are often part of the Mycobacterium tuberculosis complex (MTC) maintenance community, complicating TB control attempts. We describe the current knowledge on global TB distribution and the significance of wildlife hosts; identify insufficiently known aspects of host pathology, ecology and epidemiology; present selected time series in wildlife TB; and summarize ongoing research on TB control, providing additional insight on vaccination. Six specific research needs are identified and discussed, namely: 1) complete the world map of wildlife MTC reservoirs and describe the structure of each local MTC host community; 2) identify the origin and behaviour of generalized diseased individuals within populations, and study the role of …

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