Volta

Diagnostic performance of multiplex lateral flow tests in ambulatory patients with acute respiratory illness

Unknown authors · 2024
hash_id: 8e21f7ddf4d9e619cfc9578c52b64e5e955220da5e81bce4a7bd66df2cbbe8ee · DOI: 10.1016/j.diagmicrobio.2024.116421

We assessed the performance of three different multiplex lateral flow assays manufactured by SureScreen, Microprofit and Goldsite which provide results for influenza, respiratory syncytial virus (RSV) and SARS-CoV-2. Between 4 April and 20 October 2023, 1646 patients 6 months and older presenting to an outpatient department of a hospital in Hong Kong with ≥2 symptoms or signs of an acute respiratory illness were enrolled. The point estimates for all three multiplex tests had sensitivity >80% for influenza A and SARS-CoV-2 compared to PCR, and the tests manufactured by Microprofit and Goldsite had sensitivity >84% to detect RSV. Specificity was >97% for all three tests except for the SureScreen test which had specificity 86.2% (95% CI: 83.9% to 88.3%) for influenza …

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Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection secondary