Volta

Sex Differences in Modifiable Risk Factors and Severity of Coronary Artery Disease

Unknown authors · 2020
hash_id: 9082c9a1740b7911199c1de377ad8931931f78dfa80cb1a5ae36ec0d9c9e6702 · DOI: 10.1161/jaha.120.017235

Background It is still unknown whether traditional risk factors may have a sex‐specific impact on coronary artery disease (CAD) burden. Methods and Results We identified 14 793 patients who underwent coronary angiography for acute coronary syndromes in the ISACS‐TC (International Survey of Acute Coronary Syndromes in Transitional Countries; Clini​calTr​ials.gov , NCT01218776) registry from 2010 to 2019. The main outcome measure was the association between traditional risk factors and severity of CAD and its relationship with 30‐day mortality. Relative risk (RR) ratios and 95% CIs were calculated from the ratio of the absolute risks of women versus men using inverse probability of weighting. Estimates were compared by test of interaction on the log scale. Severity of CAD was categorized as obstructive …

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The Real Contribution of the Major Risk Factors to the Coronary Epidemics secondary