Volta

Comparative Analysis of Flight Volume Effects on COVID-19 and Influenza Transmission Across Variable Control Intensities, 2019–2024

Unknown authors · 2025
hash_id: b93401c2eb72f70f5873f371453498f7dafed43fab2aed1153401fa6b9a7a86b · DOI: 10.1093/infdis/jiaf545

BACKGROUND: Air travel has played a critical role in the global spread of infectious diseases, facilitating rapid movement of pathogens across continents. This study quantifies the effects of intercontinental flight volumes on both influenza and COVID-19 transmission patterns across countries with varying intensities of public health interventions. METHODS: We analyzed monthly global passenger numbers from January 2019 to July 2024, coupled with comprehensive surveillance data on both pathogens. Using a hierarchical Bayesian linear mixture modeling framework, we examined the relationship between flight volumes and disease activity while accounting for heterogeneity in public health and social measures. RESULTS: Our analysis reveals that increased flight volumes were significantly associated with both influenza activity and COVID-19 case and mortality rates, with Asian flight …

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