Volta

Probiotics therapy show significant improvement in obesity and neurobehavioral disorders symptoms

Unknown authors · 2023
hash_id: cd88d12a2766e11c16177bf012ad2eac67bdadf76b62354fdf09d71eaa3b3aa9 · DOI: 10.3389/fcimb.2023.1178399

Obesity is a complex metabolic disease, with cognitive impairment being an essential complication. Gut microbiota differs markedly between individuals with and without obesity. The microbial-gut-brain axis is an important pathway through which metabolic factors, such as obesity, affect the brain. Probiotics have been shown to alleviate symptoms associated with obesity and neurobehavioral disorders. In this review, we evaluated previously published studies on the effectiveness of probiotic interventions in reducing cognitive impairment, depression, and anxiety associated with obesity or a high-fat diet. Most of the probiotics studied have beneficial health effects on obesity-induced cognitive impairment and anxiety. They positively affect immune regulation, the hypothalamic-pituitary-adrenal axis, hippocampal function, intestinal mucosa protection, and glucolipid metabolism regulation. Probiotics can influence changes in the composition …

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Gut-Brain Axis in the Early Postnatal Years of Life: A Developmental Perspective secondary