Volta

Aircraft wastewater surveillance correlates with passenger SARS-CoV-2 variants detected during mandatory border testing

Introduction Global air travel plays a central role in the rapid international spread of infectious diseases, including SARS-CoV-2. While individual passenger testing has been widely used to monitor viral importation, it is resource-intensive and may miss asymptomatic cases. Aircraft wastewater surveillance has emerged as a non-invasive, scalable alternative for monitoring pathogen circulation among travelers. In this study, we evaluated the ability of aircraft wastewater to reflect SARS-CoV-2 variant distributions among passengers under real-world conditions. Methods Wastewater samples and matched clinical data were collected from 86 international flights (42 from the UK and 44 from the USA) arriving in Israel during May 2022, when mandatory SARS-CoV-2 testing of passengers was still in place. Wastewater samples were processed using standardized concentration and …

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