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A review of the fate and effects of selected low- and no-calorie sweeteners and their probabilistic risk to aquatic organisms

Unknown authors · 2026
hash_id: d3a28cdce41fd7408731f26ff22499e79dcc62d862b658da9e1576b677ddb13f · DOI: 10.1093/inteam/vjag122

Low- and no-calorie sweeteners (LNCS) are increasingly prevalent in food and beverages, with significant consumption growth in recent decades. This trend has led to heightened research into monitoring these non-nutritive sugar substitutes in environmental matrices, especially surface water. Many LNCS are excreted largely unchanged and are highly soluble in water, resulting in their detection in aquatic environments at concentrations ranging from ng/L to µg/L, primarily due to municipal or household wastewater discharge. While LNCS are generally considered safe for human consumption with established Acceptable Daily Intakes (ADI), their ecological risks remain an interest due to their global ubiquitous use, eventual entry into surface waters, and limited use of contemporary ecological risk assessment methodologies for these substances. We investigated five common …

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