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Artificial intelligence in microbial biotechnology for food security: current state and challenges

The global food system is constantly being constrained by biotic and abiotic challenges, resulting in instability and insecurity, particularly in regions like sub-Saharan Africa, where agricultural productivity often remains below global averages. Microbial biotechnology includes many sustainable ways of leveraging the metabolic potential of microorganisms, such as bacteria, fungi, and viruses, to address food insecurity through enhanced crop resilience, precision fermentation, and improved soil health. Keeping up with these demands now requires constant innovative multidisciplinary approaches in the fast-growing field of artificial intelligence (AI). AI is reinventing microbial biotechnology via various applications in the areas of taxonomic profiling, metabolic modeling, and the design of microbial cell factories. This review evaluates the transformative role of AI in optimizing these microbial systems. …

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